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Prof. Naumann

Prof. Dr. rer. nat. Michael Naumann

Medizinische Fakultät
Institut für Experimentelle Innere Medizin (IEIM)
Haus 05, Leipziger Str. 44, 39120, Magdeburg, H5/316
Tel.: +49 391 67 13227
Fax: +49 391 67 13312

Prof. Dr. rer. nat. Michael Naumann

Medizinische Fakultät
Institut für Experimentelle Innere Medizin (IEIM)
Haus 05, Leipziger Str. 44, 39120, Magdeburg, H5/316
Tel.: +49 391 67 13227
Fax: +49 391 67 13312
Projekte

Aktuelle Projekte

Abgeschlossene Projekte

Publikationen

2017

Abstrakt
Herrera-Molina, Rodrigo;  Vemula, Sampath Kumar;  Naumann, Michael;  Seidenbecher, Constanze;  Gundelfinger, Eckhard D. 

A new way to create synapses - neuroplastin-TRAF6-dependent signaling induces excitatory synapse formation
In: Journal of neurochemistry: official journal of the International Society for Neurochemistry : JN - Oxford: Wiley-Blackwell, Bd. 142.2017, Suppl. 1, MTU08-08, S. 130; http://onlinelibrary.wiley.com/doi/10.1111/jnc.2017.142.issue-S1/issuetoc

Begutachteter Zeitschriftenartikel
Korthals, Mark;  Langnaese, Kristina;  Smalla, Karl-Heinz;  Kähne, Thilo;  Herrera-Molina, Rodrigo;  Handschuh, Juliane;  Lehmann, Anne-Christin;  Mamula, Dejan;  Naumann, Michael;  Seidenbecher, Constanze;  Zuschratter, Werner;  Tedford, Kerry;  Gundelfinger, Eckhard D.;  Montag, Dirk;  Fischer, Klaus-Dieter;  Thomas, Ulrich 

A complex of neuroplastin and plasma membrane Ca2+ ATPase controls T cell activation
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, Bd. 7.2017, Art.-Nr. 8358, insges. 13 S.; http://dx.doi.org/10.1038/s41598-017-08519-4

Böge, Yannick Thimotheus;  Malehmir, Mohsen;  Healy, Marc E.;  Bettermann, Kira;  Lorentzen, Anna;  Vucur, Mihael;  Ahuja, Akshay Kumar;  Böhm, Friederike;  Mertens, Joachim C.;  Shimizu, Yutaka;  Frick, Lukas;  Remouchamps, Caroline;  Mutreja, Karun;  Kähne, Thilo;  Sundaravinayagam, Devakumar;  Wolf, Monika J.;  Rehrauer, Hubert;  Koppe, Christiane;  Speicher, Tobias;  Padrissa-Altés, Susagna;  Maire, Renaud;  Schattenberg, Jörn Markus;  Jeong, Ju-Seong;  Liu, Lei;  Zwirner, Stefan;  Boger, Regina;  Hüser, Norbert;  Davis, Roger J.;  Müllhaupt, Beat;  Moch, Holger;  Schulze-Bergkamen, Henning;  Clavien, Pierre-Alain;  Werner, Sabine;  Borsig, Lubor;  Luther, Sanjiv A.;  Jost, Philipp J.;  Weinlich, Ricardo;  Unger, Kristian;  Behrens, Axel;  Hillert, Laura;  Dillon, Christopher;  Virgilio, Michela;  Wallach, David;  Dejardin, Emmanuel;  Zender, Lars;  Naumann, Michael;  Walczak, Henning;  Green, Douglas R.;  Lopes, Massimo;  Lavrik, Inna N.;  Lüdde, Tom;  Heikenwälder, Mathias;  Weber, Achim 

A dual role of caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development
In: Cancer cell - Cambridge, Mass: Cell Press, Bd. 32.2017, 3, S. 342-359; http://dx.doi.org/10.1016/j.ccell.2017.08.010

Zimmermann, Stephanie;  Pfannkuch, Lennart;  Al-Zeer, Munir A.;  Bartfeld, Sina;  Koch, Manuel;  Liu, Jianping;  Rechner, Cindy;  Soerensen, Meike;  Sokolova, Olga;  Zamyatina, Alla;  Kosma, Paul;  Mäurer, André Germar Paul;  Glowinski, Frithjof;  Pleissner, Klaus-Peter;  Schmid, Monika;  Brinkmann, Volker;  Karlas, Alexander;  Naumann, Michael;  Rother, Marion;  Machuy, Nikolaus;  Meyer, Thomas F. 

ALPK1- and TIFA-dependent innate immune response triggered by the helicobacter pylori type IV secretion system
In: Cell reports - Maryland Heights, MO: Cell Press, Bd. 20.2017, 10, S. 2384-2395; http://dx.doi.org/10.1016/j.celrep.2017.08.039

Ranjan, Satish;  Goihl, Alexander;  Kohli, Shrey;  Gadi, Ihsan;  Pierau, Mandy;  Shahzad, Khurrum;  Gupta, Dheerendra;  Bock, Fabian Maximilian;  Wang, Hongjie;  Shaikh, Haroon;  Kähne, Thilo;  Reinhold, Dirk;  Bank, Ute;  Zenclussen, Ana Claudia;  Niemz, Jana;  Schnöder, Tina;  Brunner-Weinzierl, Monika;  Fischer, Thomas;  Kalinski, Thomas;  Schraven, Burkhart;  Luft, Thomas;  Hühn, Jochen;  Naumann, Michael;  Heidel, Florian;  Isermann, Berend 

Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells
In: Nature Communications - [London]: Nature Publishing Group UK, Bd. 8.2017, Art.-Nr. 311, insges. 16 S.; http://dx.doi.org/10.1038/s41467-017-00169-4

Dubiel, Dawadschargal;  Bintig, Willem;  Kähne, Thilo;  Dubiel, Wolfgang;  Naumann, Michael 

Cul3 neddylation is crucial for gradual lipid droplet formation during adipogenesis
In: Biochimica et biophysica acta / Molecular cell research - Amsterdam [u.a.]: Elsevier, Bd. 1864.2017, 8, S. 1405-1412; http://dx.doi.org/10.1016/j.bbamcr.2017.05.009

Yazdi, Samira;  Naumann, Michael;  Stein, Matthias 

Double phosphorylation-induced structural changes in the signal-receiving domain of I[kappa]B[alpha] in complex with NF-[kappa]B
In: Proteins: structure, function, and bioinformatics - New York, NY: Wiley-Liss, Bd. 85.2017, 1, S. 17-29; http://dx.doi.org/10.1002/prot.25181

Yazdi, Samira;  Naumann, Michael;  Stein, Matthias 

Double phosphorylation-induced structural changes in the signal-receiving domain of IκBα in complex with NF-κB
In: Proteins: Structure, Function, and Bioinformatics, 2017, S. 17-29, ISSN 08873585, 10.1002/prot.25181

Naumann, Michael;  Sokolova, Olga;  Tegtmeyer, Nicole;  Backert, Steffen 

Helicobacter pylori - a paradigm pathogen for subverting host cell signal transmission
In: Trends in microbiology - Amsterdam [u.a.]: Elsevier Science, Bd. 25.2017, 4, S. 316-328; http://dx.doi.org/10.1016/j.tim.2016.12.004

Tegtmeyer, Nicole;  Weßler, Silja;  Necchi, Vittorio;  Rohde, Manfred;  Harrer, Aileen;  Rau, Tilman Tassilo Rupert;  Asche, Carmen Isabell;  Boehm, Manja;  Lößner, Holger;  Figueiredo, Ceu;  Naumann, Michael;  Palmisano, Ralf;  Solcia, Enrico;  Ricci, Vittorio;  Backert, Steffen 

Helicobacter pylori employs a unique basolateral type IV secretion mechanism for CagA delivery
In: Cell host and microbe - Amsterdam [u.a.]: Elsevier, Bd. 22.2017, 4, S. 552-560; http://dx.doi.org/10.1016/j.chom.2017.09.005

Sokolova, Olga;  Naumann, Michael 

NF[kappa]B signaling in gastric cancer
In: Toxins - Basel: MDPI, Bd. 9.2017, 4, Art.-Nr. 119, insges. 21 S.; http://dx.doi.org/10.3390/toxins9040119

Lim, Michelle C.C.;  Maubach, Gunter;  Sokolova, Olga;  Feige, Michael H.;  Diezko, Rolf Christian;  Buchbinder, Jörn;  Backert, Steffen;  Schlüter, Dirk;  Lavrik, Inna N.;  Naumann, Michael 

Pathogen-induced ubiquitin-editing enzyme A20 bifunctionally shuts off NF-B and caspase-8-dependent apoptotic cell death
In: Cell death and differentiation - Houndmills, Basingstoke: Nature Publishing Group, Bd. 24.2017, 9, S. 1621-1631; http://dx.doi.org/10.1038/cdd.2017.89

Schmid, Ursula;  Stenzel, Werner;  Koschel, Josephin;  Raptaki, Maria;  Wang, Xu;  Naumann, Michael;  Matuschewski, Kai;  Schlüter, Dirk;  Nishanth, Gopala 

The deubiquitinating enzyme cylindromatosis dampens CD8+ T cell responses and is a critical factor for experimental cerebral malaria and bloodbrain barrier damage
In: Frontiers in immunology - Lausanne: Frontiers Media, Bd. 8.2017, Art.-Nr. 27, insges. 17 S.; http://dx.doi.org/10.3389/fimmu.2017.00027

2016

Abstrakt
Lim, Michelle;  Maubach, Gunter;  Diezko, Rolf;  Sokolova, Olga;  Feige, Michael;  Buchbinder, Jörn;  Lavrik, Inna;  Naumann, Michael 

NF-KappaB dependent expression of a20 controls cell death in H. pylori-infected cells
In: Helicobacter. - Oxford [u.a.] : Wiley-Blackwell; Bd. 21.2016, Suppl. 1, Abs. P09.03, S. 162

Begutachteter Zeitschriftenartikel
Just, Sissy;  Nishanth, Gopala;  Buchbinder, Jörn H.;  Wang, Xu;  Naumann, Michael;  Lavrik, Inna;  Schlüter, Dirk 

A20 curtails primary but augments secondary CD8+ T cell responses in intracellular bacterial infection
In: Scientific reports. - London : Nature Publishing Group; Bd. 6.2016, Art.-Nr. 39796, insges. 15 S.

Kolodziej, Angela;  Smalla, Karl-Heinz;  Richter, Sandra;  Engler, Alexander;  Pielot, Rainer;  Dieterich, Daniela C.;  Tischmeyer, Wolfgang;  Naumann, Michael;  Kähne, Thilo 

High resolution quantitative synaptic proteome profiling of mouse brain regions after auditory discrimination learning. Video article
In: Journal of visualized experiments : JoVE. - [S.l.]; Bd. 118 (2016), Art.-Nr. e54992, insges. 12 S.

Oh, In Soo;  Textoris-Taube, Kathrin;  Sung, Pil Soo;  Kang, Wonseok;  Gorny, Xenia;  Kähne, Thilo;  Hong, Seon-Hui;  Choi, Young Joon;  Cammann, Clemens;  Naumann, Michael;  Kim, Jong Hoon;  Park, Su-Hyung;  Yoo, Ook Joon;  Kloetzel, Peter M.;  Seifert, Ulrike;  Shin, Eui-Cheol 

Immunoproteasome induction is suppressed in hepatitis C virus-infected cells in a protein kinase R-dependent manner
In: Experimental and molecular medicine: EMM - Seoul: Soc, Bd. 48.2016, Art.-Nr. e270, insges. 10 S., 48 2016 10 Bd. 48.2016, Art.-Nr. e270, insges. 10 S.; http://dx.doi.org/10.1038/emm.2016.98

Schleich, Kolja;  Buchbinder, Jörn H.;  Pietkiewicz, Sabine;  Kähne, Thilo;  Warnken, Uwe;  Öztürk, Selcen;  Schnölzer, Martina;  Naumann, Michael;  Krammer, Peter H.;  Lavrik, Inna 

Molecular architecture of the DED chains at the DISC - regulation of procaspase-8 activation by short DED proteins c-FLIP and procaspase-8 prodomain
In: Cell death and differentiation. - Houndmills, Basingstoke : Nature Publishing Group, Bd. 23.2016, 4, S. 681-694

Gummlich, Linda;  Kähne, Thilo;  Naumann, Michael;  Kilic, Ergin;  Jung, Klaus;  Dubiel, Wolfgang 

New insights into the mechanism of COP9 signalosomecullin-RING ubiquitin-ligase pathway deregulation in urological cancers
In: International review of cell and molecular biology. - Amsterdam [u.a.] : Elsevier, Bd. 323.2016, S. 181-229

Backert, Steffen;  Neddermann, Matthias;  Maubach, Gunter;  Naumann, Michael 

Pathogenesis of Helicobacter pylori infection
In: Helicobacter. - Oxford [u.a.] : Wiley-Blackwell; Bd. 21 (2016), Suppl.1, Seite 19-25

Kähne, Thilo;  Richter, Sandra;  Kolodziej, Angela;  Smalla, Karl-Heinz;  Pielot, Rainer;  Engler, Alexander;  Ohl, Frank W.;  Dieterich, Daniela C.;  Seidenbecher, Constanze;  Tischmeyer, Wolfgang;  Naumann, Michael;  Gundelfinger, Eckart D. 

Proteome rearrangements after auditory learning - high-resolution profiling of synapse-enriched protein fractions from mouse brain
In: Journal of neurochemistry : official journal of the International Society for Neurochemistry ; JN. - Oxford : Wiley-Blackwell, Bd. 138.2016, 1, S. 124-138

Wex, Katharina;  Schmid, Ursula;  Just, Sissy;  Wang, Xu;  Wurm, Rebecca;  Naumann, Michael;  Schlüter, Dirk;  Nishanth, Gopala 

Receptor-interacting protein kinase-2 inhibition by CYLD impairs antibacterial immune responses in macrophages
In: Frontiers in immunology. - Lausanne : Frontiers Media; Bd. 6.2016, Art.-Nr. 650, insges. 13 S.

Schweitzer, Katrin;  Pralow, Alexander;  Naumann, Michael 

p97/VCP promotes Cullin-RING-ubiquitin-ligase/proteasome-dependent degradation of IBα and the preceding liberation of RelA from ubiquitinated IBα
In: Journal of cellular and molecular medicine : an international journal ; JCMM. - Hoboken, NJ : Wiley-Blackwell, Bd. 20.2016, 1, S. 58-70

Nicht begutachteter Zeitschriftenartikel
Braun-Dullaeus, Rüdiger C. 

Das internistische Jahr 2015 - die wichtigsten Fortschritte und Entwicklungen
In: Ärzteblatt Sachsen-Anhalt : offizielles Mitteilungsblatt der Ärztekammer Sachsen-Anhalt. - Magdeburg : Ärztekammer Sachsen-Anhalt, Bd. 27.2016, 5, S. 19-22

2015

Abstrakt
Naumann, Michael;  Feige, M.;  Sokolova, Olga 

The role of Helicobacter pylori-induced canonical- and non-canonical NF-KB signaling in cell survival
In: Helicobacter. - Oxford [u.a.] : Wiley-Blackwell; Bd. 20.2015, Suppl. 1, Abs. P04.18, S. 108-109

Begutachteter Zeitschriftenartikel
Xuan, Nguyen Thi;  Wang, Xu;  Nishanth, Gopala;  Waisman, Ari;  Borucki, Katrin;  Isermann, Berend;  Naumann, Michael;  Deckert, Martina;  Schlüter, Dirk 

A20 expression in dendritic cells protects mice from LPS-induced mortality
In: European journal of immunology. - Weinheim : Wiley-VCH, Bd. 45.2015, 3, S. 818-828

Dubiel, Dawadschargal;  Ordemann, Jürgen;  Pratschke, Johann;  Dubiel, Wolfgang;  Naumann, Michael 

CAND1 exchange factor promotes Keap1 integration into cullin 3-RING ubiquitin ligase during adipogenesis
In: International journal of biochemistry & cell biology. - Amsterdam : Elsevier, Bd. 66.2015, S. 95-100

Schweitzer, Katrin;  Naumann, Michael 

CSN-associated USP48 confers stability to nuclear NF-[kappa]B/RelA by trimming K48-linked Ub-chains
In: Biochimica et biophysica acta / Molecular cell research. - Amsterdam [u.a.] : Elsevier, Bd. 1853.2015, 2, S. 453-469

Medunjanin, Senad;  Daniel, Jan-Marcus;  Weinert, Sönke;  Dutzmann, Jochen;  Burgbacher, Frank;  Brecht, Sarah;  Brümmer, Dennis;  Kähne, Thilo;  Naumann, Michael;  Sedding, Daniel G.;  Zuschratter, Werner;  Braun-Dullaeus, Ruediger C. 

DNA-dependent protein kinase (DNA-PK) permits vascular smooth muscle cell proliferation through phosphorylation of the orphan nuclear receptor NOR1
In: Cardiovascular research. - Oxford : Oxford University Press, Bd. 106.2015, 3, S. 488-497

Reichenbach, Nicole;  Herrmann, Ulrike;  Kähne, Thilo;  Schicknick, Horst;  Pielot, Rainer;  Naumann, Michael;  Dieterich, Daniela C.;  Gundelfinger, Eckart D.;  Smalla, Karl-Heinz;  Tischmeyer, Wolfgang 

Differential effects of dopamine signalling on long-term memory formation and consolidation in rodent brain
In: Proteome science : PS. - London : BioMed Central; Bd. 13.2015, Art.-Nr.13, insges. 17 S.

Dubiel, Dawadschargal;  Rockel, Beate;  Naumann, Michael;  Dubiel, Wolfgang 

Diversity of COP9 signalosome structures and functional consequences
In: FEBS letters : for the rapid publication of short reports in biochemistry, biophysics, and molecular biology. - Amsterdam [u.a.] : Elsevier; Bd. 589.2015, 19 Pt.A, S. 2507-2513

Wurm, Rebecca;  Just, Sissy;  Wang, Xu;  Wex, Katharina;  Schmid, Ursula;  Blanchard, Nicolas;  Waisman, Ari;  Schild, Hans-Jörg;  Naumann, Michael;  Schlüter, Dirk;  Nishanth, Gopala 

Protective dendritic cell responses against listeriosis induced by the short form of the deubiquitinating enzyme CYLD are inhibited by full-length CYLD
In: European journal of immunology. - Weinheim : Wiley-VCH, Bd. 45.2015, 5, S. 1366-1376

Schmidt, Jörn H.;  Pietkiewicz, Sabine;  Naumann, Michael;  Lavrik, Inna N. 

Quantification of CD95-induced apoptosis and NF-[Kappa]B activation at the single cell level
In: Journal of immunological methods : JIM. - Amsterdam [u.a.] : Elsevier Science, Bd. 423.2015, S. 12-17

Dorosz, Susann A.;  Ginolhac, Aurélien;  Kähne, Thilo;  Naumann, Michael;  Sauter, Thomas;  Salsmann, Alexandre;  Bueb, Jean-Luc 

Role of calprotectin as a modulator of the IL27-mediated proinflammatory effect on endothelial cells
In: Mediators of inflammation. - Sylvania, Ohio : Hindawi Publishing Corp; 2015, Art.-ID 737310, insges. 16 S.

Yazdi, Samira;  Durdagi, Serdar;  Naumann, Michael;  Stein, Matthias 

Structural modeling of the N-terminal signal-receiving domain of I[kappa]B[alpha]
In: Frontiers in molecular biosciences. - Lausanne : Frontiers; Bd. 2.2015, Art.-Nr. 32, insges. 16 S.

2014

Abstrakt
Schnöder, Tina M.;  Pandey, Akhilesh Datt;  Nimmagadda, Subbaiah Chery;  Wang, Xu;  Maubach, Gunter;  Wolleschak, Denise;  Naumann, Michael;  Schlüter, Dirk;  Lane, Steven W.;  Mullally, Ann;  Heidel, Florian H.;  Fischer, Thomas 

JAK2V617F mutation is sufficient for autocrine induction of IP-10 in hematopoietic cells
In: Oncology research and treatment. - Basel : Karger; Bd. 37.2014, Suppl. 5, V618, S. 199

Begutachteter Zeitschriftenartikel
Flassig, Robert J.;  Maubach, Gunter;  Täger, Christian;  Sundmacher, Kai;  Naumann, Michael 

Experimental design, validation and computational modeling uncover DNA damage sensing by DNA-PK and ATM
In: Molecular BioSystems. - Cambridge : Royal Society of Chemistry, Bd. 10.2014, 7, S. 1978-1986

Sokolova, Olga;  Vieth, Michael;  Gnad, Thorsten;  Bozko, Przemyslaw M.;  Naumann, Michael 

Helicobacter pylori promotes eukaryotic protein translation by activating phosphatidylinositol 3 kinase/mTOR
In: International journal of biochemistry & cell biology. - Amsterdam : Elsevier, Bd. 55.2014, S. 157-163

Sokolova, Olga;  Maubach, Gunter;  Naumann, Michael 

MEKK3 and TAK1 synergize to activate IKK complex in Helicobacter pylori infection
In: Biochimica et biophysica acta. - Amsterdam [u.a.] : ElsevierBiochimica et biophysica acta / Molecular cell research, Bd. 1843.2014, 4, S. 715-724

2013

Begutachteter Zeitschriftenartikel
Wang, Xu;  Deckert, Martina;  Xuan, Nguyen Thi;  Nishanth, Gopala;  Just, Sissy;  Waisman, Ari;  Naumann, Michael;  Schlüter, Dirk 

Astrocytic A20 ameliorates experimental autoimmune encephalomyelitis by inhibiting NF-[kappa]B- and STAT1-dependent chemokine production in astrocytes
In: Acta neuropathologica. - Berlin : Springer, Bd. 126.2013, 5, S. 711-724

Dubiel, Dawadschargal;  Gierisch, Maria Elka;  Huang, Xiaohua;  Dubiel, Wolfgang;  Naumann, Michael 

CAND1-dependent control of cullin 1-RING Ub ligases is essential for adipogenesis
In: Biochimica et biophysica acta. - Amsterdam [u.a.] : Elsevier, Bd. 1833.2013, 5, S. 1078-1084

Maubach, Gunter;  Sokolova, Olga;  Wolfien, Markus;  Rothkötter, Hermann-Josef;  Naumann, Michael 

Ca2+/calmodulin-dependent kinase II contributes to inhibitor of nuclear factor-kappa B kinase complex activation in Helicobacter pylori infection
In: International journal of cancer. - Malden, Mass : Wiley-Blackwell, Bd. 133.2013, 6, S. 1507-1512

Lee, Jung-Hoon;  Yi, Lina;  Li, Jixi;  Schweitzer, Katrin;  Borgmann, Marc;  Naumann, Michael;  Wu, Hao 

Crystal structure and versatile functional roles of the COP9 signalosome subunit 1
In: Proceedings of the National Academy of Sciences of the United States of America. - Washington, DC : NAS, Bd. 110.2013, 29, S. 11845-11850

Karpova, Anna;  Mikhaylova, Marina;  Bera, Sujoy;  Bär, Julia;  Reddy, Pasham Parameshwar;  Behnisch, Thomas;  Rankovic, Vladan;  Spilker, Christina;  Bethge, Philipp;  Sahin, Jale;  Kaushik, Rahul;  Zuschratter, Werner;  Kähne, Thilo;  Naumann, Michael;  Gundelfinger, Eckart D.;  Kreutz, Michael R. 

Encoding and transducing the synaptic or extrasynaptic origin of NMDA receptor signals to the nucleus
In: Cell. - Cambridge, Mass : Cell Press, Bd. 152.2013, 5, S. 1119-1133

Sokolova, Olga;  Borgmann, Marc;  Rieke, Cornelia;  Schweitzer, Katrin;  Rothkötter, Hermann-Josef;  Naumann, Michael 

Helicobacter pylori induces type 4 secretion system-dependent, but CagA-independent activation of I[kappa]Bs and NF-[kappa]B/RelA at early time points
In: International journal of medical microbiology. - München : Elsevier, Bd. 303.2013, 8, S. 548-552

Sokolova, Olga;  Vieth, Michael;  Naumann, Michael 

Protein kinase C isozymes regulate matrix metalloproteinase-1 expression and cell invasion in Helicobacter pylori infection
In: Gut. - London : BMJ Publishing Group, Bd. 62.2013, 3, S. 358-367

Diesing, Anne-Kathrin;  Nossol, Constanze;  Faber-Zuschratter, Heidi;  Zuschratter, Werner;  Renner, Lydia;  Sokolova, Olga;  Naumann, Michael;  Rothkötter, Hermann-Josef 

Rapid interaction of Helicobacter pylori with microvilli of the polar human gastric epithelial cell line NCI-N87
In: The anatomical record. - Hoboken, NJ : Wiley-Liss; Bd. 296.2013, 12, S. C1

Diesing, Anne-Kathrin;  Nossol, Constanze;  Faber-Zuschratter, Heidi;  Zuschratter, Werner;  Renner, Lydia;  Sokolova, Olga;  Naumann, Michael;  Rothkötter, Hermann-Josef 

Rapid interaction of Helicobacter pylori with microvilli of the polar human gastric epithelial cell line NCI-N87
In: The anatomical record. - Hoboken, NJ : Wiley-Liss, Bd. 296.2013, 12, S. 1800-1805

Originalartikel in begutachteter internationaler Zeitschrift
Nishanth, Gopala;  Deckert, Martina;  Wex, Katharina;  Massoumi, Ramin;  Schweitzer, Katrin;  Naumann, Michael;  Schlüter, Dirk 

CYLD enhances severe listeriosis by impairing IL-6/STAT3-dependent fibrin production
In: PLoS pathogens. - Lawrence, Kan : PLoS; Bd. 9.2013, 6, Art. e1003455, insges. 17 S.

2012

Originalartikel in begutachteter internationaler Zeitschrift
Buss, Holger;  Handschick, Katja;  Jurrmann, Nadine;  Pekkonen, Pirita;  Beuerlein, Knut;  Müller, Helmut;  Wait, Robin;  Saklatvala, Jeremy;  Ojala, Päivi M.;  Schmitz, M. Lienhard;  Naumann, Michael;  Kracht, Michael 

Cyclin-dependent kinase 6 phosphorylates NF-[kappa]B p65 at serine 536 and contributes to the regulation of inflammatory gene expression
In: PLoS one. - Lawrence, Kan : PLoS, Bd. 7.2012, 12, insges. 13 S.

Kähne, Thilo;  Kolodziej, Angela;  Smalla, Karl-Heinz;  Eisenschmidt, Elke;  Haus, Utz-Uwe;  Weismantel, Robert;  Kropf, Siegfried;  Wetzel, Wolfram;  Ohl, Frank W.;  Tischmeyer, Wolfgang;  Naumann, Michael;  Gundelfinger, Eckart D. 

Synaptic proteome changes in mouse brain regions upon auditory discrimination learning
In: Proteomics. - Weinheim : Wiley-Blackwell, Bd. 12.2012, 15/16, S. 2433-2444

2011

Nicht begutachteter Zeitschriftenartikel
Naumann, Michael 

Therapierelevante Forschung in der Inneren Medizin
In: Ärzteblatt Sachsen-Anhalt. - Magdeburg : Ärztekammer Sachsen-Anhalt, Bd. 22.2011, 4, S. 25-26

Originalartikel in begutachteter internationaler Zeitschrift
Rieke, Cornelia;  Papendieck, Anja;  Sokolova, Olga;  Naumann, Michael 

Helicobacter pylori-induced tyrosine phosphorylation of IKK[beta] contributes to NF-[kappa]B activation
In: Biological chemistry. - Berlin [u.a.] : de Gruyter, Bd. 392.2011, 4, S. 387-393

Neish, Andrew S.;  Naumann, Michael 

Microbial-induced immunomodulation by targeting the NF-[Kappa]B system
In: Trends in microbiology. - Cambridge : Elsevier, Bd. 19.2011, 12, S. 596-605

2010

Originalartikel in begutachteter internationaler Zeitschrift
Schweitzer, Katrin;  Naumann, Michael 

Control of NF-[kappa]B activation by the COP9 signalosome
In: Biochemical Society : Biochemical Society transactions . - London : Portland Pr., Bd. 38.2010, 1, S. 156-161

Cama, Gianluca;  Jacobs, Thomas;  Dimaki, Maria I.;  Svendsen, Winnie E.;  Hauptmann, Peter;  Naumann, Michael 

Disposable micro-fluidic biosensor array for online parallelized cell adhesion kinetics analysis on quartz crystal resonators
In: Measurement science and technology . - Bristol : IOP Publ. Ltd., Bd. 21.2010, 8, insges. 12 S.

Rollié, Sascha;  Lendeckel, Uwe;  Naumann, Michael;  Reichl, Udo;  Sundmacher, Kai 

Dynamics of bionanoparticle targeting in mixtures of human tumour cells by validated population balance modelling
In: Soft matter. - Cambridge : RSC Publ, Bd. 6.2010, 6, S. 1203-1216

Schweitzer, Katrin;  Sokolova, Olga;  Bozko, Przemyslaw M.;  Naumann, Michael 

Helicobacter pylori induces NF-[kappa]B independent of CagA. Correspondence
In: European Molecular Biology Organization : EMBO reports . - London : Nature Publ. Group, Bd. 11.2010, 1, S. 10-11

Gnad, Thorsten;  Feoktistova, Maria;  Leverkus, Martin;  Lendeckel, Uwe;  Naumann, Michael 

Helicobacter pylori-induced activation of [beta]-catenin involves low density lipoprotein receptor-related protein 6 and dishevelled
In: Molecular cancer . - London : Biomed Central, Bd. 9.2010, 31, insges. 9 S.; Abstract unter URL: http://www.molecular-cancer.com/content/9/1/31

Wex, Thomas;  Leodolter, Andreas;  Bornschein, Jan;  Küster, Dörthe;  Kähne, Thilo;  Kropf, Siegfried;  Albrecht, Caroline;  Naumann, Michael;  Roessner, Albert;  Malfertheiner, Peter 

Interleukin 1 beta (IL1B) gene polymorphisms are not associated with gastric carcinogenesis in Germany
In: Anticancer research . - Kapandriti : International Inst. of Anticancer Research, Bd. 30.2010, 2, S. 505-511

Rieke, Cornelia;  Kähne, Thilo;  Schweitzer, Katrin;  Schraven, Burkhart;  Wienands, Jürgen;  Engelke, Michael;  Naumann, Michael 

Non-T cell activation linker regulates ERK activation in Helicobacter pylori-infected epithelial cells
In: Cellular signalling . - Amsterdam : Elsevier, Bd. 22.2010, 3, S. 395-403

Mirastschijski, Ursula;  Schnabel, Reinhild;  Naumann, Michael;  Kähne, Thilo 

Novel plant metalloproteinase from Dieffenbachia seguine causes fingertip necrosis. Correspondence
In: The British journal of dermatology . - Oxford : Wiley-Blackwell, Bd. 162.2010, 5, S. 1150-1152

Nishanth, Gopala;  Sakowicz-Burkiewicz, Monika;  Händel, Ulrike;  Kliche, Stefanie;  Wang, Xiaoqian;  Naumann, Michael;  Deckert, Martina;  Schlüter, Dirk 

Protective toxoplasma gondii-specific T-cell responses require T-cell-specific expression of protein kinase C-theta
In: Infection and immunity . - Washington, DC : Soc., Bd. 78.2010, 8, S. 3454-3464

Valero, Teresa;  Moschopoulou, Georgia;  Kintzios, Spiridon;  Hauptmann, Peter;  Naumann, Michael;  Jacobs, Thomas 

Studies on neuronal differentiation and signalling processes with a novel impedimetric biosensor
In: Biosensors & bioelectronics . - Barking, Essex : Elsevier, Bd. 26.2010, 4, S. 1407-1413

Backert, Steffen;  Naumann, Michael 

What a disorder: proinflammatory signaling pathways induced by Helicobacter pylori
In: Trends in microbiology . - Cambridge : Elsevier, Bd. 18.2010, 11, S. 479-486

2009

Originalartikel in begutachteter internationaler Zeitschrift
Heidel, Florian;  Lipka, Daniel;  Mirea, Fian K.;  Mahboobi, Siavosh;  Grundler, Rebekka;  Kancha, Rama K.;  Duyster, Justus;  Naumann, Michael;  Huber, Christoph;  Böhmer, Frank D.;  Fischer, Thomas 

Bis(1H-indol-2-yl)methanones are effective inhibitors of FLT3-ITD tyrosine kinase and partially overcome resistance to PKC412A in vitro
In: British journal of haematology . - Oxford [u.a.] : Wiley-Blackwell, Bd. 144.2009, 6, S. 865-874

Welteke, Verena;  Eitelhuber, Andrea;  Düwel, Michael;  Schweitzer, Katrin;  Naumann, Michael;  Krappmann, Daniel 

COP9 signalosome controls the Carma1-Bcl10-Malt1 complex upon T-cell stimulation
In: European Molecular Biology Organization : EMBO reports . - London : Nature Publ. Group, Bd. 10.2009, 6, S. 642-648

Schirrmeister, Wiebke;  Gnad, Thorsten;  Wex, Thomas;  Higashiyama, Shigeki;  Wolke, Carmen;  Naumann, Michael;  Lendeckel, Uwe 

Ectodomain shedding of E-cadherin and c-Met is induced by Helicobacter pylori infection
In: Experimental cell research . - San Diego, Calif. : Elsevier, Bd. 315.2009, 20, S. 3500-3508

Valero, Teresa;  Jacobs, Thomas;  Moschopoulou, Georgia;  Naumann, Michael;  Hauptmann, Peter;  Kintzios, Spiridon 

Electrical impedance analysis of N2a neuroblastoma cells in gel matrices after ACh-receptor triggering with an impedimetric biosensor
In: Procedia chemistry . - Amsterdam [u.a.] : Elsevier, Bd. 1.2009, 1, S. 734-737; Abstract unter URL: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B983C-4X49BRW-6J&_user=1908396&_coverDate=08%2F31%2F2009&_rdoc=184&_fmt=high&_orig=browse&_srch=doc-info(%23toc%2359039%232009%23999989998%231477108%23FLP%23display%23Volume)&_cdi=59039&_sort=d&_docanchor=&view=c&_ct=386&_acct=C000052693&_version=1&_urlVersion=0&_userid=1908396&md5=b9dfb860025be4e6f091063eb78293cf ; [Proceedings of the Eurosensors XXIII Conference]

Jacobs, Thomas;  Valero, Teresa;  Naumann, Michael;  Kintzios, Spiridon;  Hauptmann, Peter 

Electrical impedance spectroscopy of gel embedded neuronal cells based on a novel impedimetric biosensor
In: Procedia chemistry . - Amsterdam [u.a.] : Elsevier, Bd. 1.2009, 1, S. 261-264; Abstract unter URL: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B983C-4X49BRW-2B&_user=1908396&_coverDate=08%2F31%2F2009&_rdoc=66&_fmt=high&_orig=browse&_srch=doc-info(%23toc%2359039%232009%23999989998%231477108%23FLP%23display%23Volume)&_cdi=59039&_sort=d&_docanchor=&_ct=386&_acct=C000052693&_version=1&_urlVersion=0&_userid=1908396&md5=f95ea7708e66d5622b05bc30e5cfd316 ; [Proceedings of the Eurosensors XXIII Conference]

Walduck, Anna K.;  Weber, Matthias;  Wunder, Christian;  Jüttner, Stefan;  Stolte, Manfred;  Vieth, Michael;  Wiedenmann, Bertram;  Meyer, Thomas F.;  Naumann, Michael;  Höcker, Michael 

Identification of novel Cyclooxygenase-2-dependent genes in Helicobacter pylori infection in vivo
In: Molecular cancer . - London : Biomed Central, Bd. 8.2009, 22, insges. 13 S.; Abstract unter URL: http://www.molecular-cancer.com/content/8/1/22

Jacobs, Thomas;  Cama, Gianluca;  Bolaeva, Kermen;  Naumann, Michael;  Hauptmann, Peter 

Impact of flow-through regime on the cultivation of epithelial cells on quartz crystal resonators in micro fluidic channels
In: Procedia chemistry . - Amsterdam [u.a.] : Elsevier, Bd. 1.2009, 1, S. 365-368; Abstract unter URL: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B983C-4X49BRW-38&_user=1908396&_coverDate=08%2F31%2F2009&_rdoc=92&_fmt=high&_orig=browse&_srch=doc-info(%23toc%2359039%232009%23999989998%231477108%23FLP%23display%23Volume)&_cdi=59039&_sort=d&_docanchor=&_ct=386&_acct=C000052693&_version=1&_urlVersion=0&_userid=1908396&md5=af571ba4f908ca901055a24ad8828c88 ; [Proceedings of the Eurosensors XXIII Conference]

Cama, Gianluca;  Bolaeva, Kermen;  Jacobs, Thomas;  Hartmann, Matthias;  Hirsch, Sören;  Naumann, Michael;  Hauptmann, Peter 

Influence of statistical variations in cell distribution on the proliferation kinetics of Madin-Darby canine kidney cells on quartz crystal resonator
In: Procedia chemistry. - Amsterdam [u.a.] : Elsevier, Bd. 1.2009, 1, S. 373-376

Poltz, Rainer;  Franke, Raimo;  Schweitzer, Katrin;  Klamt, Steffen;  Gilles, Ernst-Dieter;  Naumann, Michael 

Logical network of genotoxic stress-induced NF-[kappa]B signal transduction predicts putative target structures for therapeutic intervention strategies
In: Advances and applications in bioinformatics and chemistry . - Albany, Auckland : Dove Medical Press, Bd. 2.2009, S. 125-138; Abstract unter URL: http://www.dovepress.com/logical-network-of-genotoxic-stress-induced-nf-kappab-signal-transduct-peer-reviewed-article-AABC

Originalartikel in begutachteter zeitschriftenartiger Reihe
Jacobs, Thomas;  Valero, Teresa;  Naumann, Michael;  Kintzios, Spiridon;  Hauptmann, Peter 

Impedimetric biosensor system for the on-line analysis of stimulated neuronal cells embedded in gel matrices
In: IEEE Sensors 2009 . - IEEE, ISBN 978-1-424-45335-1, S. 1864-1867 ; Kongress: IEEE Conference on Sensors; 8 (Christchurch) : 2009.10.25-28 ; [Auch auf CD-ROM erschienen]

2008

Originalartikel in begutachteter internationaler Zeitschrift
Xia, Guoqing;  Schneider-Stock, Regine;  Diestel, Antje;  Habold, Caroline;  Krüger, Sabine;  Roessner, Albert;  Naumann, Michael;  Lendeckel, Uwe 

Helicobacter pylori regulates p21WAF1 by histone H4 acetylation
In: Biochemical and biophysical research communications . - San Diego, Calif. : Elsevier, ISSN 0006-291x, Bd. 369.2008, 2, S. 526-531

Sokolova, Olga;  Bozko, Przemyslaw M.;  Naumann, Michael 

Helicobacter pylori suppresses glycogen synthase kinase 3[beta] to promote [beta]-catenin activity
In: The journal of biological chemistry . - Bethesda, Md. : ASBMB, Bd. 283.2008, 43, S. 29367-29374

Franke, Raimo;  Müller, Melanie;  Wundrack, Nicole;  Gilles, Ernst-Dieter;  Klamt, Steffen;  Kähne, Thilo;  Naumann, Michael 

Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transduction
In: BMC systems biology . - London : BioMed Central, Bd. 2.2008, 4, insges. 17 S.; Abstract unter URL: http://www.biomedcentral.com/1752-0509/2/4

Sakowicz-Burkiewicz, Monika;  Nishanth, Gopala;  Helmuth, Ulrike;  Drögemüller, Katrin;  Busch, Dirk H.;  Utermöhlen, Olaf;  Naumann, Michael;  Deckert, Martina;  Schlüter, Dirk 

Protein kinase C-[theta] critically regulates the proliferation and survival of pathogen-specific T cells in murine listeriosis
In: The journal of immunology . - Bethesda, Md. : American Assoc. of Immunologists, Bd. 180.2008, 8, S. 5601-5612

Originalartikel in begutachteter zeitschriftenartiger Reihe
Jacobs, Thomas;  Cama, Gianluca;  Hartmann, Matthias;  Kähne, Thilo;  Hirsch, Sören;  Naumann, Michael;  Hauptmann, Peter 

Disposable micro fluidic biosensor array for parallelized online cell stimulation analysis
In: Proceedings // Eurosensors XXII. - Düsseldorf : VDI/VDE-Ges. Mess- und Automatisierungstechnik, S. 1189-1192, 2008 ; Kongress: Eurosensors; 22 (Dresden) : 2008.09.07-10[Beitrag auf CD-ROM]

Jacobs, Thomas;  Cama, Gianluca;  Hartmann, Matthias;  Kähne, Thilo;  Hirsch, Sören;  Naumann, Michael;  Hauptmann, Peter 

Micro fluidic biosensor array for parallelized cell adhesion analysis during pathogenic infection
In: IEEE sensors 2008, S. 1460-1463 ; Kongress: IEEE Conference on Sensors; 7 (Lecce, Italy) : 2008.10.26-29[Beitrag auf CD-ROM]

Jacobs, Thomas;  Bolaeva, Kermen;  Kähne, Thilo;  Naumann, Michael;  Hauptmann, Peter 

Online adhesion analysis of hepatocyte growth factor stimulated cells with resonant biosensor
In: Proceedings // Eurosensors XXII . - Düsseldorf : VDI/VDE-Ges. Mess- und Automatisierungstechnik, ISBN 978-3-00-025217-4, S. 1185-1188, 2008 ; Kongress: Eurosensors; 22 (Dresden) : 2008.09.07-10

Jacobs, Thomas;  Bolaeva, Kermen;  Kähne, Thilo;  Naumann, Michael;  Hauptmann, Peter 

Real-time analysis of hepatocyte growth factor induced cell motility with quartz crystal resonators
In: IEEE sensors 2008 : the 7th IEEE Conference on Sensors ; Lecce, Italy, October 26-29, 2008, S. 246-249 ; Kongress: IEEE Conference on Sensors; 7 (Lecce, Italy) : 2008.10.26-29[Beitrag auf CD-ROM]

2007

Buchbeitrag
Wex, Thomas;  Sokic-Milutinovic, Aleksandra;  Kalinski, Thomas;  Roessner, Albert;  Malfertheiner, Peter;  Naumann, Michael;  Lendeckel, Uwe 

Expression of ADAM19 in Helicobacter pylori-mediated diseases and gastric cancer
In: Gastric cancer research trends . - New York : Nova Science, ISBN 978-1-600-21725-8, S. 171-188, 2007

Originalartikel in begutachteter internationaler Zeitschrift
Neumann, Manfred;  Naumann, Michael 

Beyond I[kappa]Bs: alternative regulation of NF-[kappa]B activity
In: Federation of American Societies for Experimental Biology : The FASEB journal . - Bethesda, Md. : FASEB, Bd. 21.2007, 11, S. 2642-2654

Schweitzer, Katrin;  Bozko, Przemyslaw M.;  Dubiel, Wolfgang;  Naumann, Michael 

CSN controls NF-[kappa]B by deubiquitinylation of I[kappa]B[alpha]
In: European Molecular Biology Organization : The EMBO journal . - London : Nature Publ. Group, Bd. 26.2007, 6, S. 1532-1541

Bimczok, Diane;  Rau, Henriette;  Wundrack, Nicole;  Naumann, Michael;  Rothkötter, Hermann-Josef;  McCullough, Kenneth;  Summerfield, Artur 

Cholera toxin promotes the generation of semi-mature porcine monocyte-derived dendritic cells that are unable to stimulate T cells
In: Veterinary research . - Paris : Ed.Scientifiques Elsevier, Bd. 38.2007, 4, S. 597-612

Naumann, Michael 

Control of the NF-[kappa]B inhibitor I[kappa]B[alpha] in pathogen infection
In: Biochemical Society : Biochemical Society transactions . - London : Portland Pr., Bd. 35.2007, 2, S. 267-269

Bank, Ute;  Tadje, Janine;  Täger, Michael;  Wolke, Carmen;  Bukowska, Alicja;  Ittenson, Annelore;  Reinhold, Dirk;  Helmuth, Martin;  Ansorge, Siegfried;  Shakespeare, Ann;  Vieth, Michael;  Malfertheiner, Peter;  Naumann, Michael;  Lendeckel, Uwe 

Inhibition of alanyl-aminopeptidase on CD4+CD25+ regulatory T-cells enhances expression of FoxP3 and TGF-[beta]1 and ameliorates acute colitis in mice
In: International journal of molecular medicine . - Athens, Bd. 20.2007, 4, S. 483-492

Lippert, E.;  Falk, W.;  Bataille, F.;  Kähne, Thilo;  Naumann, Michael;  Goeke, M.;  Herfarth, H.;  Schoelmerich, J.;  Rogler, G. 

Soluble galectin-3 is a strong, colonic epithelial-cell-derived, lamina propria fibroblast-stimulating factor
In: Gut . - London : BMJ Publishing Group, Bd. 56.2007, 1, S. 43-51

Stork, Björn;  Neumann, Konstantin;  Goldbeck, Ingo;  Alers, Sebastian;  Kähne, Thilo;  Naumann, Michael;  Engelke, Michael;  Wienands, Jürgen 

Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca2+ signaling in B cells
In: European Molecular Biology Organization : The EMBO journal . - London : Nature Publ. Group, Bd. 26.2007, 4, S. 1140-1149

Bimczok, Diane;  Döll, Susanne;  Rau, Henriette;  Goyarts, Tanja;  Wundrack, Nicole;  Naumann, Michael;  Dänicke, Sven;  Rothkötter, Hermann-Josef 

The Fusarium toxin deoxynivalenol disrupts phenotype and function of monocyte-derived dendritic cells in vivo and in vitro
In: Immunobiology . - Amsterdam : Elsevier, Bd. 212.2007, 8, S. 655-666

Originalartikel in begutachteter zeitschriftenartiger Reihe
Jacobs, Thomas;  Gomide, Andreza;  Kähne, Thilo;  Kienle, Achim;  Naumann, Michael;  Hauptmann, Peter 

Micro fluidic biosensor system based on quartz crystal resonators for fast online adherent cell proliferation and stimulation analysis
In: IEEE sensors 2007 conference, S. 720-723

2006

Originalartikel in begutachteter internationaler Zeitschrift
Crabtree, Jean E.;  Naumann, Michael 

Epithelial cell signaling in Helicobacter pylori infection
In: Current signal transduction therapy . - San Francisco, Calif. [u.a.] : Bentham Science Publ., Bd. 1.2006, 1, S. 53-65

Krüger, Sabine;  Hundertmark, Tanja;  Kalinski, Thomas;  Peitz, Ulrich;  Wex, Thomas;  Malfertheiner, Peter;  Naumann, Michael;  Roessner, Albert 

Helicobacter pylori encoding the pathogenicity island activates matrix-metalloproteinase 1 in gastric epithelial cells via JNK and ERK
In: The journal of biological chemistry . - Bethesda, Md. : ASBMB, Bd. 281.2006, 5, S. 2868-2875

Neumann, Manfred;  Foryst-Ludwig, Anna;  Klar, Stefanie;  Schweitzer, Katrin;  Naumann, Michael 

The PAK1 autoregulatory domain is required for interaction with NIK in Helicobacter pylori-induced NF-[kappa]B activation
In: Biological chemistry . - Berlin [u.a.] : de Gruyter, Bd. 387.2006, 1, S. 79-86

2005

Buchbeitrag
Naumann, Michael;  Crabtree, J. (ext.) 

Helicobacter pylori mechanisms for inducing epithelial cell proliferation.
In: Lax, A. (Ed.): Bacterial protein toxins : role in the interference with cell growth regulation. Cambridge ; New York : Cambridge Univ. Press, 2005, S. 169 - 198 (Advances in molecular and cellular microbiology ; 7)

Originalartikel in begutachteter internationaler Zeitschrift
Huang, X. (ext.);  Hetfeld, B. (ext.);  Seifert, U. (ext.);  Kaehne, Thilo;  Kloetzel, P.M. (ext.);  Naumann, Michael;  Bech-Otschir, D. (ext.);  Dubiel, W. (ext.) 

Consequences of COP9 signalosome and 26S proteasome interaction.
In: FEBS J. 272(2005), Nr. 15, S. 3909 - 3917

Drynda, Andreas;  Quax, P. (ext.);  Neumann, Manfred;  Laan, W.van der (ext.);  Pap, Geza;  Drynda, Susanne;  Meinecke, I. (ext.);  Kekow, Joern;  Neumann, W. (ext.);  Huizinga, T. (ext.);  Naumann, Michael;  Koenig, Wolfgang;  Pap, T. (ext.) 

Gene transfer of tissue inhibitor of metalloproteinases-3 reverses the inhibitory effects of TNF-alpha on Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
In: J. Immunol. 174(2005), Nr. 10, S. 6524 - 6531

Malfertheiner, Peter;  Sipponen, P. (ext.);  Naumann, Michael;  Moayyedi, P. (ext.);  Megraud, F. (ext.);  Xiao, S.D. (ext.) 

Helicobacter pylori eradication has the potential to prevent gastric cancer : a state-of-the- art critique.
In: Am. J. Gastroenterol. 100(2005), Nr. 9, S. 2100 - 2115

Hollenbach, Eike;  Vieth, Michael W.R.;  Roessner, Albert;  Neumann, Manfred;  Malfertheiner, Peter;  Naumann, Michael 

Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease.
In: J. Biol. Chem. 280(2005), Nr. 15, S. 14981 - 14988

Naumann, Michael 

Pathogenicity island-dependent effects of Helicobacter pylori on intracellular signal transduction in epithelial cells.
In: Int. J. Med. Microbiol. 295(2005), Nr. 5, S. 335 - 341

Wessler, S. (ext.);  Muenzner, P. (ext.);  Meyer, T. (ext.);  Naumann, Michael 

The anti-inflammatory compound curcumin inhibits Neisseria gonorrhoeae-induced NF-kappaB signaling, release of pro-inflammatory cytokines/chemokines and attenuates adhesion in late infection.
In: Biol. Chem. 386(2005), Nr. 5, S. 481 - 490

Krueger, Sabine;  Kalinski, Thomas;  Hundertmark, Tanja;  Wex, Thomas;  Kuester, Doerthe;  Peitz, Ulrich;  Ebert, Matthias;  Naegler, D. (ext.);  Kellner, U. (ext.);  Malfertheiner, Peter;  Naumann, Michael;  Roecken, Christoph;  Roessner, Albert 

Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer.
In: J. Pathol. 207(2005), Nr. 1, S. 32 - 42

2004

Originalartikel in begutachteter internationaler Zeitschrift
Al-Ghoul, L.;  Wessler, Silja;  Hundertmark, Tanja;  Krueger, Sabine;  Fischer, W. (ext.);  Wunder, C. (ext.);  Haas, R. (ext.);  Roessner, Albert;  Naumann, Michael 

Analysis of the type IV secretion system-dependent cell motility of Helicobacter pylori- infected epithelial cells.
In: Biochem. Biophys. Res. Commun. 322(2004), Nr. 3, S. 860 - 866

Foryst-Ludwig, Anna;  Neumann, Manfred;  Schneider-Brachert, W. (ext.);  Naumann, Michael 

Curcumin blocks NF-kappaB and the motogenic response in Helicobacter pylori-infected epithelial cells.
In: Biochem. Biophys. Res. Commun. 316(2004), Nr. 4, S. 1065 - 1072

Naumann, Michael;  Crabtree, J. (ext.) 

Helicobacter pylori-induced epithelial cell signalling in gastric carcinogenesis.
In: Trends Microbiol. 12(2004), Nr. 1, S. 29 - 36

Hollenbach, Eike;  Neumann, Manfred;  Vieth, Michael W.R.;  Roessner, Albert;  Malfertheiner, Peter;  Naumann, Michael 

Inhibition of p38 MAP kinase- and RICK/NF-kappaB-signaling suppresses inflammatory bowel disease.
In: Faseb J. 18(2004), S. 1550 - 1552

Leodolter, Andreas;  Naumann, Michael;  Malfertheiner, Peter 

Prevention of gastric cancer by Helicobacter pylori eradication.
In: Dig. Dis. 22(2004), Nr. 4, S. 313 - 319

2003

Originalartikel in begutachteter internationaler Zeitschrift
Zhou, C. (ext.);  Wee, S. (ext.);  Rhee, E. (ext.);  Naumann, Michael;  Dubiel, W. (ext.);  Wolf, D. (ext.) 

Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p.
In: Mol. Cell 11(2003), S. 927 - 938

Churin, Y. (ext.);  Al-Ghoul, L.;  Kepp, O. (ext.);  Meyer, T. (ext.);  Birchmeier, W. (ext.);  Naumann, Michael 

Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response.
In: J. Cell Biol. 161(2003), Nr. 2, S. 249 - 255

Juettner, S. (ext.);  Cramer, T. (ext.);  Wessler, Silja;  Walduck, A. (ext.);  Naumann, Michael;  Hoecker, M. (ext.);   

Helicobacter pylori stimulates host cyclooxygenase-2 gene transcription : critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factors.
In: Cell. Microbiol. 5(2003), Nr. 11, S. 821 - 834

Strowski, M. (ext.);  Cramer, T. (ext.);  Schaefer, G. (ext.);  Wessler, Silja;  Naumann, Michael;  Hoecker, M. (ext.);  ;   

Helicobacter pylori stimulates host vascular endothelial growth factor-A (vegf-A) gene expression via MEK/ERK-dependent activation of Sp1 and Sp3. . - Gedr. ersch. in: FASEB J. 18(2004)1, S. 218 - 220.
In: Faseb J.(2003)

Hollenbach, Eike;  Naumann, Michael;  Malfertheiner, Peter 

The mitogen-activated protein kinase p38 : a new molecular target for anti-inflammatory therapy in Crohn's disease?.
In: Gastroenterol. Polska 10(2003), Nr. 4, S. 335 - 340

2002

Originalartikel in begutachteter internationaler Zeitschrift
Gerhard, M. (ext.);  Rad, R. (ext.);  Prinz, C. (ext.);  Naumann, Michael 

Pathogenesis of Helicobacter pylori infection.
In: Helicobacter 7(2002), Suppl. 1, S. 17 - 23

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Zellbiologie
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  • Magenkrebs Präventionsforschung
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  • Zelluläre Infektionsbiologie Helicobacter pylori
  • Magenkrebs Präventionsforschung
  • Multiproteinkomplex (COP9)
Vita
presse
Das Institut kooperiert mit den Kliniken des Zentrums für Innere Medizin in Lehre und Forschung. Die Studierenden werden in den Studiengängen Medizin und Biosystems-Engineering ausgebildet. Das Forschungsprogramm des Instituts umfasst wissenschaftliche Projekte zur Pathophysiologie von Entzündungen und Tumorbiologie. Hier sind die molekularen und zellbiologische Mechanismen der intrazellulären Signalübertragung von besonderem Interesse. Darüber hinaus arbeiten die Arbeitsgruppen auf die Frage der Funktion von Proteinen in zellulären Netzwerken und dem innovativen Ansatz von mathematischen Modellen des Signals Prozesse in komplexen Systemen.

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